Expert Biological Data Analysis Services
Data-Driven Research Solutions for Your Biological Data
Need Expert Biological Data Analysis?
AltraBio specializes in biological data analysis, helping you unlock insights from cytometry, omics, and medical data using AI and advanced statistics.
We serve as a research and development partner for leading companies and university hospitals across various sectors, including pharmaceuticals, medical devices, diagnostics, and dermo-cosmetics.
Learn more about our services:
Our Biological Data Analysis Expertise
Partnerships
Development of computational tools for biological data analysis in regional, national, and international consortia.
Examples of our current and completed projects include:
Subcontracting
Biological data analysis services for companies and university hospitals.
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Hundreds of completed projects.
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Our regular customers include top 10 pharmaceutical companies and leaders in cosmetics.
Why Choose AltraBio for Biological Data Analysis?
« Supervised approach is really a mature approach, I think there is an absolute need for having this solution… »
« The quality of the results we got from AB was quite remarkable in the good »
« AltraBio is viewed as automating subject matter experts, with the ability to do the same work. It allows us to free up subject matter experts at scale so a subject matter expert doesn’t have to spend as much time doing gating or reviewing gatings, and it all hinges on the quality that they provide. So for us, that’s the biggest selling point; the quality allow us to be able to say, OK this technology is almost as good as subject matter experts in this domain, and the pricing and the speed make it such that it becomes a feasible solution for us to say we can free up the scientists to do other things and this part can be handled by AltraBio. »
« Even in the age of generative AI, Altrabio’s two decades of expertise in maths, stats, biology, and medical science remain invaluable. They don’t just talk, they do. No flashy marketing, no inflated costs, just solid, thoughtful work from study design to actionable insights. A trusted partner, for twenty years, in a world full of noise. Highly recommend working with them to make real sense of your complex biomedical and omics data. »
« They do cutting-edge work, we clearly like the innovation part »
« In clinical trials, we could get thousands of samples for different panels… The scale is clearly so big, not many companies can do this kind of work in production mode, on the labor scale »
« They fit clients’ need. »
« Exceptional »
« We really appreciate AltraBio because they provide one-stop full service, so we don’t need to worry about a lot of former problems, and also quality of results »
« Automated gating is there… In 2018, when automated gating was discussed at CYTO, some people stood up and said: “No! This is not going to work. Gating has been done by scientists & experts, and you can’t just put a computer to do their job.” We know now that it is not true because the Altrabio’s solutions are now doing it. It is pretty amazing. »
« This is accurate; we can use it at scale, so we don’t have to do the manual gating. »
« They do that extra bit of QC on their hand; they also check the transfers and put that extra effort in to make sure that what we do is accurate »
« The work we do with AltraBio is a partnership. I’ll make an example of the last analysis that we did; there were some timelines that needed to be met and they stepped in and said “OK we‘ll get this done in a few days”, not in a week, not in a month … When you have that relationship, when you understand the value and you understand the timelines of the customer, that felt really like a partnership and I think we’re heading in that direction… »
« Top of the field »
« They are highly efficient and agile; you won’t interact with much people, so they are quick to respond and provide high-quality service »
« If there is some problem, or troubleshooting is necessary, or some change in the workflow, they are very flexible.»
Discover how our tailored solutions in biological data analysis can accelerate your R&D projects.
News
March 2026
Dermocosmetics Omics Analysis: AltraBio at Cosmetotest
The international symposium Cosmetotest is a premier event dedicated [...]
saRNA Vaccine Transcriptomics: Insights from the COVAC1 Trial
The COVID-19 pandemic highlighted RNA vaccination as a rapid [...]
February 2026
SNV Analysis Pipeline for Clownfish Genetics | AltraBio Case Study
Animal pigmentation patterns are essential for survival and behavior. [...]
Machine Learning Identifies Key IPF Prognostic Biomarkers in ISABELA Trials
Introduction A major study recently published in ERJ Open [...]
Latest Publications
2014
Samarut, Eric; Gaudin, Cyril; Hughes, Sandrine; Gillet, Benjamin; Bernard, Simon; Jouve, Pierre-Emmanuel; Buffat, Laurent; Allot, Alexis; Lecompte, Odile; Berekelya, Liubov; Rochette-Egly, Cécile; Laudet, Vincent
Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo Journal Article
In: Mol. Endocrinol., vol. 28, no. 2, pp. 260–272, 2014.
@article{Samarut2014-my,
title = {Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo},
author = {Eric Samarut and Cyril Gaudin and Sandrine Hughes and Benjamin Gillet and Simon Bernard and Pierre-Emmanuel Jouve and Laurent Buffat and Alexis Allot and Odile Lecompte and Liubov Berekelya and Cécile Rochette-Egly and Vincent Laudet},
doi = {10.1210/me.2013-1358},
year = {2014},
date = {2014-02-01},
urldate = {2014-02-01},
journal = {Mol. Endocrinol.},
volume = {28},
number = {2},
pages = {260--272},
publisher = {The Endocrine Society},
abstract = {Retinoic acid (RA) controls many aspects of embryonic
development by binding to specific receptors (retinoic acid
receptors [RARs]) that regulate complex transcriptional
networks. Three different RAR subtypes are present in
vertebrates and play both common and specific roles in
transducing RA signaling. Specific activities of each receptor
subtype can be correlated with its exclusive expression pattern,
whereas shared activities between different subtypes are
generally assimilated to functional redundancy. However, the
question remains whether some subtype-specific activity still
exists in regions or organs coexpressing multiple RAR subtypes.
We tackled this issue at the transcriptional level using early
zebrafish embryo as a model. Using morpholino knockdown, we
specifically invalidated the zebrafish endogenous RAR subtypes
in an in vivo context. After building up a list of RA-responsive
genes in the zebrafish gastrula through a whole-transcriptome
analysis, we compared this panel of genes with those that still
respond to RA in embryos lacking one or another RAR subtype. Our
work reveals that RAR subtypes do not have fully redundant
functions at the transcriptional level but can transduce RA
signal in a subtype-specific fashion. As a result, we define RAR
subtype-specific transcriptotypes that correspond to repertoires
of genes activated by different RAR subtypes. Finally, we found
genes of the RA pathway (cyp26a1, raraa) the regulation of which
by RA is highly robust and can even resist the knockdown of all
RARs. This suggests that RA-responsive genes are differentially
sensitive to alterations in the RA pathway and, in particular,
cyp26a1 and raraa are under a high pressure to maintain
signaling integrity.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
development by binding to specific receptors (retinoic acid
receptors [RARs]) that regulate complex transcriptional
networks. Three different RAR subtypes are present in
vertebrates and play both common and specific roles in
transducing RA signaling. Specific activities of each receptor
subtype can be correlated with its exclusive expression pattern,
whereas shared activities between different subtypes are
generally assimilated to functional redundancy. However, the
question remains whether some subtype-specific activity still
exists in regions or organs coexpressing multiple RAR subtypes.
We tackled this issue at the transcriptional level using early
zebrafish embryo as a model. Using morpholino knockdown, we
specifically invalidated the zebrafish endogenous RAR subtypes
in an in vivo context. After building up a list of RA-responsive
genes in the zebrafish gastrula through a whole-transcriptome
analysis, we compared this panel of genes with those that still
respond to RA in embryos lacking one or another RAR subtype. Our
work reveals that RAR subtypes do not have fully redundant
functions at the transcriptional level but can transduce RA
signal in a subtype-specific fashion. As a result, we define RAR
subtype-specific transcriptotypes that correspond to repertoires
of genes activated by different RAR subtypes. Finally, we found
genes of the RA pathway (cyp26a1, raraa) the regulation of which
by RA is highly robust and can even resist the knockdown of all
RARs. This suggests that RA-responsive genes are differentially
sensitive to alterations in the RA pathway and, in particular,
cyp26a1 and raraa are under a high pressure to maintain
signaling integrity.
Samarut, Eric; Gaudin, Cyril; Hughes, Sandrine; Gillet, Benjamin; de Bernard, Simon; Jouve, Pierre-Emmanuel; Buffat, Laurent; Allot, Alexis; Lecompte, Odile; Berekelya, Liubov; Rochette-Egly, Cécile; Laudet, Vincent
Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo Journal Article
In: Mol Endocrinol, vol. 28, no. 2, pp. 260–272, 2014, ISSN: 1944-9917.
@article{pmid24422634,
title = {Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo},
author = {Eric Samarut and Cyril Gaudin and Sandrine Hughes and Benjamin Gillet and Simon de Bernard and Pierre-Emmanuel Jouve and Laurent Buffat and Alexis Allot and Odile Lecompte and Liubov Berekelya and Cécile Rochette-Egly and Vincent Laudet},
doi = {10.1210/me.2013-1358},
issn = {1944-9917},
year = {2014},
date = {2014-02-01},
urldate = {2014-02-01},
journal = {Mol Endocrinol},
volume = {28},
number = {2},
pages = {260--272},
abstract = {Retinoic acid (RA) controls many aspects of embryonic development by binding to specific receptors (retinoic acid receptors [RARs]) that regulate complex transcriptional networks. Three different RAR subtypes are present in vertebrates and play both common and specific roles in transducing RA signaling. Specific activities of each receptor subtype can be correlated with its exclusive expression pattern, whereas shared activities between different subtypes are generally assimilated to functional redundancy. However, the question remains whether some subtype-specific activity still exists in regions or organs coexpressing multiple RAR subtypes. We tackled this issue at the transcriptional level using early zebrafish embryo as a model. Using morpholino knockdown, we specifically invalidated the zebrafish endogenous RAR subtypes in an in vivo context. After building up a list of RA-responsive genes in the zebrafish gastrula through a whole-transcriptome analysis, we compared this panel of genes with those that still respond to RA in embryos lacking one or another RAR subtype. Our work reveals that RAR subtypes do not have fully redundant functions at the transcriptional level but can transduce RA signal in a subtype-specific fashion. As a result, we define RAR subtype-specific transcriptotypes that correspond to repertoires of genes activated by different RAR subtypes. Finally, we found genes of the RA pathway (cyp26a1, raraa) the regulation of which by RA is highly robust and can even resist the knockdown of all RARs. This suggests that RA-responsive genes are differentially sensitive to alterations in the RA pathway and, in particular, cyp26a1 and raraa are under a high pressure to maintain signaling integrity.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Faugaret, Delphine; Amara, Amira Ben; Alingrin, Julie; Daumas, Aurélie; Delaby, Amélie; Lépolard, Catherine; Raoult, Didier; Textoris, Julien; Mège, Jean-Louis
Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis Journal Article
In: Front Cell Infect Microbiol, vol. 4, pp. 172, 2014, ISSN: 2235-2988.
@article{pmid25566510,
title = {Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis},
author = {Delphine Faugaret and Amira Ben Amara and Julie Alingrin and Aurélie Daumas and Amélie Delaby and Catherine Lépolard and Didier Raoult and Julien Textoris and Jean-Louis Mège},
doi = {10.3389/fcimb.2014.00172},
issn = {2235-2988},
year = {2014},
date = {2014-01-01},
urldate = {2014-01-01},
journal = {Front Cell Infect Microbiol},
volume = {4},
pages = {172},
abstract = {The formation of granulomas is associated with the resolution of Q fever, a zoonosis due to Coxiella burnetii; however the molecular mechanisms of granuloma formation remain poorly understood. We generated human granulomas with peripheral blood mononuclear cells (PBMCs) and beads coated with C. burnetii, using BCG extracts as controls. A microarray analysis showed dramatic changes in gene expression in granuloma cells of which more than 50% were commonly modulated genes in response to C. burnetii and BCG. They included M1-related genes and genes related to chemotaxis. The inhibition of the chemokines, CCL2 and CCL5, directly interfered with granuloma formation. C. burnetii granulomas also expressed a specific transcriptional profile that was essentially enriched in genes associated with type I interferon response. Our results showed that granuloma formation is associated with a core of transcriptional response based on inflammatory genes. The specific granulomatous response to C. burnetii is characterized by the activation of type 1 interferon pathway.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Funding
