Simon de Bernard

Ph.D. (Biochimie et Biologie Moléculaire) et diplômé de l'"École Polytechnique", la plus prestigieuse école d'ingénieurs de France. Simon possède plusieurs années d'expérience en recherche industrielle dans le domaine des biotechnologies comme chef de projets chez ValiGen (France, Paris) et chef de projets sénior chez IT.Omics (Lille, France).

Publications

MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis. Bauer Y, White ES, de Bernard S, Cornelisse P, Leconte I, Morganti A, Roux S, Nayler O. ERJ Open Res. 2017 Mar; 3(1).

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge. Blanc P, Moro-Sibilot L, Barthly L, Jagot F, This S, de Bernard S, Buffat L, Dussurgey S, Colisson R, Hobeika E, Fest T, Taillardet M, Thaunat O, Sicard A, Mondière P, Genestier L, Nutt SL, Defrance T. Nat Commun. 2016 Dec; 7:13600.

Immune signatures of protective spleen memory CD8 T cells. Brinza L, Djebali S, Tomkowiak M, Mafille J, Loiseau C, Jouve PE, de Bernard S, Buffat L, Lina B, Ottmann M, Rosa-Calatrava M, Schicklin S, Bonnefoy N, Lauvau G, Grau M, Wencker M, Arpin C, Walzer T, Leverrier Y, Marvel J.  Sci Rep. 2016 Nov; 6:37651.

CD1d-restricted peripheral T cell lymphoma in mice and humans. Bachy E, Urb M, Chandra S, Robinot R, Bricard G, de Bernard S, Traverse-Glehen A, Gazzo S, Blond O, Khurana A, Baseggio L, Heavican T, Ffrench M, Crispatzu G, Mondière P, Schrader A, Taillardet M, Thaunat O, Martin N, Dalle S, Le Garff-Tavernier M, Salles G, Lachuer J, Hermine O, Asnafi V, Roussel M, Lamy T, Herling M, Iqbal J, Buffat L, Marche PN, Gaulard P, Kronenberg M, Defrance T, Genestier L. J Exp Med. 2016 May; 213(5):841-57.

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection. van Helden MJ, Goossens S, Daussy C, Mathieu AL, Faure F, Marçais A, Vandamme N, Farla N, Mayol K, Viel S, Degouve S, Debien E, Seuntjens E, Conidi A, Chaix J, Mangeot P, de Bernard S, Buffat L, Haigh JJ, Huylebroeck D, Lambrecht BN, Berx G, Walzer T. J Exp Med. 2015 Nov;212(12):2015-25.

Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib. Idbaih A, Mokhtari K, Emile JF, Galanaud D, Belaid H, de Bernard S, Benameur N, Barlog VC, Psimaras D, Donadieu J, Carpentier C, Martin-Duverneuil N, Haroche J, Feuvret L, Zahr N, Delattre JY, Hoang-Xuan K. Neurology. 2014 Oct;83(16):1478-80.

A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis. Bauer Y, Tedrow J, de Bernard S, Birker-Robaczewska M, Gibson KF, Guardela BJ, Hess P, Klenk A, Lindell KO, Poirey S, Renault B, Rey M, Weber E, Nayler O, Kaminski N. Am J Respir Cell Mol Biol. 2015 Feb;52(2):217-31.

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. Daussy C, Faure F, Mayol K, Viel S, Gasteiger G, Charrier E, Bienvenu J, Henry T, Debien E, Hasan UA, Marvel J, Yoh K, Takahashi S, Prinz I, de Bernard S, Buffat L, Walzer T. J Exp Med. 2014 Mar;211(3):563-77.

Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo. Samarut E, Gaudin C, Hughes S, Gillet B, de Bernard S, Jouve PE, Buffat L, Allot A, Lecompte O, Berekelya L, Rochette-Egly C, Laudet V. Mol Endocrinol. 2014 Feb;28(2):260-72.

Differentially expressed androgen-regulated genes in androgen-sensitive tissues reveal potential biomarkers of early prostate cancer. Altintas DM, Allioli N, Decaussin M, de Bernard S, Ruffion A, Samarut J, Vlaeminck-Guillem V. PLoS One. 2013 Jun;8(6):e66278.

SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas. Idbaih A, Ducray F, Dehais C, Courdy C, Carpentier C, de Bernard S, Uro-Coste E, Mokhtari K, Jouvet A, Honnorat J, Chinot O, Ramirez C, Beauchesne P, Benouaich-Amiel A, Godard J, Eimer S, Parker F, Lechapt-Zalcman E, Colin P, Loussouarn D, Faillot T, Dam-Hieu P, Elouadhani-Hamdi S, Bauchet L, Langlois O, Le Guerinel C, Fontaine D, Vauleon E, Menei P, Fotso MJ, Desenclos C, Verrelle P, Ghiringhelli F, Noel G, Labrousse F, Carpentier A, Dhermain F, Delattre JY, Figarella-Branger D; POLA Network. PLoS One. 2012;7(10):e45950.

Biological pathways and networks in pharma discovery strategies: From information source to innovative insight. Hradecky P, de Bernard S, Stanislawski P, Buffat L. European Biopharma Review. 2005 (Spring) 70-4.

Sequential cleavage and excision of a segment of the thyrotropin receptor ectodomain. de Bernard S, Misrahi M, Huet JC, Beau I, Desroches A, Loosfelt H, Pichon C, Pernollet JC, Milgrom E. J Biol Chem. 1999 Jan;274(1):101-7.

Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain. Couët J, de Bernard S, Loosfelt H, Saunier B, Milgrom E, Misrahi M. Biochemistry. 1996 Nov;35(47):14800-5.